Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688078 | 0.95 | GPR119 (0.56) | GPR119EGLN2CHRM4PDK2FAAH | |
| SCHEMBL29475535 | 0.87 | GPR119 (0.59) | GPR119PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL25317704 | 0.87 | GPR119 (0.59) | GPR119PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL5235667 | 0.86 | ALDH1A1 (0.57) | GPR119EGLN2PDK2FAAHALDH1A1 | |
| SCHEMBL3487620 | 0.85 | GPR119 (0.72) | GPR119CHRM4NOTUM | |
| SCHEMBL7372018 | 0.84 | GPR119 (0.57) | GPR119EGLN2PDK2ALDH1A1LMNA | |
| SCHEMBL25317395 | 0.84 | GPR119 (0.62) | GPR119PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL29475574 | 0.84 | GPR119 (0.62) | GPR119PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL15584576 | 0.83 | GPR119 (0.56) | GPR119PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL24216358 | 0.83 | GPR119 (0.56) | GPR119EGLN2PDK2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |