Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 11/20 | 0.75 |
| ▸ | ADK | P55263 | 8/20 | 0.70 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.70 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.70 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.70 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.70 |
| ▸ | CDK1 | P06493 | 1/20 | 0.70 |
| ▸ | ROS1 | P08922 | 1/20 | 0.70 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | FLT3 | P36888 | 1/20 | 0.70 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.70 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.70 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.70 |
| ▸ | MELK | Q14680 | 1/20 | 0.70 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.70 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142206 | 1.00 | ATG7 (0.75) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20142733 | 0.92 | ATG7 (0.75) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20142323 | 0.92 | ATG7 (0.75) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20141857 | 0.87 | ATG7 (0.73) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20142559 | 0.87 | ATG7 (0.73) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20141611 | 0.86 | ATG7 (1.00) | ATG7 | |
| SCHEMBL20142554 | 0.85 | ATG7 (0.74) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20141694 | 0.85 | ATG7 (0.74) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20141717 | 0.84 | ATG7 (0.72) | ATG7ADKDOT1LDCLK1DAPK3 | |
| SCHEMBL20142577 | 0.84 | ATG7 (0.72) | ATG7ADKDOT1LDCLK1DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865208-B2 | ATG7 inhibitors and the uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865208-B2 | ATG7 inhibitors and the uses thereof | ATG7, BECN1, SQSTM1 | ATG7 1/4885ADK 2059/4885DOT1L 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.