Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360311 | 0.83 | RET (0.49) | CHRM4DPP4CTSK | |
| SCHEMBL16993975 | 0.82 | GAA (0.52) | — | |
| SCHEMBL31042527 | 0.81 | DRD4 (0.51) | CHRM4MTORRPTORMLST8USP30 | |
| SCHEMBL7716779 | 0.81 | CHRM4 (0.47) | CHRM4MTORRPTORMLST8FFAR4 | |
| SCHEMBL12836043 | 0.79 | CTSK (0.52) | DPP4CTSK | |
| SCHEMBL20133586 | 0.79 | MTOR (0.68) | CHRM4MTORRPTORMLST8FFAR4 | |
| Hydrochloric Acid SCHEMBL20141665 | 0.78 | MTOR (0.67) | CHRM4MTORRPTORMLST8FFAR4 | |
| SCHEMBL12836527 | 0.77 | MTOR (0.44) | CHRM4MTORRPTORMLST8USP30 | |
| SCHEMBL20140959 | 0.77 | MTOR (0.55) | CHRM4MTORRPTORMLST8FFAR4 | |
| SCHEMBL21360337 | 0.76 | CHRM4 (0.43) | CHRM4FFAR4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |