Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.46 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715922 | 0.83 | DRD4 (0.47) | CHRM4MTORRPTORMLST8DPP4 | |
| SCHEMBL7716783 | 0.82 | CHRM4 (0.45) | CHRM4MTORRPTORMLST8DPP4 | |
| SCHEMBL20141678 | 0.81 | CHRM4 (0.50) | CHRM4MTORRPTORMLST8DPP4 | |
| SCHEMBL20150022 | 0.80 | HTR1D (0.48) | CHRM4MTORRPTORMLST8DPP4 | |
| SCHEMBL7711280 | 0.80 | ALDH1A1 (0.44) | VCPSMN1; SMN2 | |
| SCHEMBL7714679 | 0.78 | CHRM4 (0.49) | CHRM4MTORRPTORMLST8DPP4 | |
| SCHEMBL7717203 | 0.76 | DRD2 (0.43) | CHRM4MTORRPTORMLST8DPP4 | |
| Hydrochloric Acid SCHEMBL1514368 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2 | |
| SCHEMBL21360337 | 0.76 | CHRM4 (0.43) | CHRM4DPP4FFAR4 | |
| SCHEMBL21360311 | 0.75 | RET (0.49) | CHRM4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |