Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129620 | 1.00 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3FPR2SCN9A | |
| SCHEMBL20141695 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL26669471 | 0.71 | HRH1 (0.36) | — | |
| SCHEMBL6645271 | 0.70 | TAAR1 (0.41) | TAAR1 | |
| Hydrochloric Acid SCHEMBL26600847 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL7427141 | 0.69 | HTR3A (0.45) | — | |
| SCHEMBL3834096 | 0.68 | TDP1 (0.35) | SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL3428166 | 0.67 | — | — | |
| SCHEMBL4389112 | 0.67 | — | — | |
| SCHEMBL1837073 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |