Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ASPH | Q12797 | 2/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.50 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21226799 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1ASPHKDM8RIOX2 | |
| SCHEMBL20132427 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1ASPHKDM8RIOX2 | |
| SCHEMBL20132456 | 0.87 | MAPK1 (0.50) | KDM4EALDH1A1MAPK1HDAC3HDAC1 | |
| SCHEMBL26697537 | 0.83 | HDAC3 (0.65) | KDM4EASPHKDM8RIOX2HDAC3 | |
| SCHEMBL20132369 | 0.83 | HDAC3 (0.65) | KDM4EASPHKDM8RIOX2HDAC3 | |
| SCHEMBL20132370 | 0.83 | HDAC3 (0.65) | KDM4EASPHKDM8RIOX2HDAC3 | |
| SCHEMBL24316097 | 0.78 | MAPK1 (0.57) | KDM4EALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL11399034 | 0.76 | P4HTM (0.56) | KDM4EALDH1A1ASPHKDM8RIOX2 | |
| SCHEMBL26698513 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1MAPK1HDAC3HDAC1 | |
| SCHEMBL20209435 | 0.74 | MAPK14 (0.53) | KDM4EASPHKDM8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538084-A1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | Acetylon Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089651-A1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | ACETYLON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |