SCHEMBL20142379

SCHEMBL20142379

CC(C)(C)OC(=O)N1CCN(c2ccc(F)cc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
MAPT P10636 2/20 0.67
LMNA P02545 1/20 0.67
ALOX15 P16050 1/20 0.59
GPR119 Q8TDV5 7/20 0.59
NAMPT P43490 1/20 0.57
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CYP2C19 P33261 1/20 0.55
PDK2 Q15119 1/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
TSHR P16473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941160 0.96 ALDH1A1 (0.62) ALDH1A1MAPTLMNAALOX15GPR119
SCHEMBL5230610 0.94 ALDH1A1 (0.61) ALDH1A1MAPTLMNAALOX15GPR119
SCHEMBL5573222 0.92 MAPT (0.76) ALDH1A1MAPTLMNAGPR119NAMPT
SCHEMBL485724 0.88 MAPK1 (0.54) ALDH1A1MAPTLMNAALOX15GPR119
SCHEMBL17807228 0.87 MAPT (0.62) ALDH1A1MAPTLMNAALOX15GPR119
SCHEMBL381360 0.86 MAPT (0.68) ALDH1A1MAPTLMNAGPR119NAMPT
SCHEMBL2056118 0.86 GPR119 (0.77) ALDH1A1MAPTLMNAGPR119NAMPT
SCHEMBL29080217 0.86 MEN1 (0.54) ALDH1A1MAPTLMNAALOX15GPR119
SCHEMBL1459696 0.85 MAPT (0.64) ALDH1A1MAPTLMNAGPR119NAMPT
SCHEMBL8257643 0.85 MAPT (0.64) ALDH1A1MAPTLMNAGPR119NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722203-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2026-04-08 EP disclosed
WO-2025109563-A1 SPIRO-HYDANTOIN DERIVATIVE EXHIBITING ADAMTS-4 INHIBITORY ACTIVITY, AND USE THEREOF 서울대학교병원 2025-05-30 WO disclosed
WO-2024251080-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国人民解放军军事科学院军事医学研究院 2024-12-12 WO disclosed
WO-2022222995-A1 PICOLINAMIDE COMPOUND 南京明德新药研发有限公司 2022-10-27 WO disclosed
EP-3538091-A1 PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF Navitor Pharmaceuticals, Inc. (US) 2019-09-18 EP disclosed
WO-2018089499-A1 PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF NAVITOR PHARMACEUTICALS, INC. (US) 2018-05-17 WO disclosed