Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996805 | 0.79 | TSHR (0.54) | TSHRTDP1SLC6A3MAPK1KMT2A | |
| SCHEMBL30368697 | 0.76 | PRSS1 (0.45) | PRSS1CTSGCTRB1CMA1TSHR | |
| SCHEMBL28638750 | 0.76 | TSHR (0.50) | TSHRTDP1MAPK1POLBNPC1 | |
| SCHEMBL8858245 | 0.76 | TDP1 (0.54) | PRSS1CTSGCTRB1CMA1TSHR | |
| SCHEMBL444012 | 0.74 | MAPK1 (0.71) | TSHRTDP1HTR1ACYP2D6SCN1A | |
| SCHEMBL998239 | 0.74 | TSHR (0.56) | TSHRTDP1SLC6A3MAPK1KMT2A | |
| SCHEMBL6504485 | 0.73 | TSHR (0.50) | TSHRTDP1SLC6A3MAPK1KMT2A | |
| SCHEMBL6504482 | 0.73 | TSHR (0.50) | TSHRTDP1SLC6A3MAPK1KMT2A | |
| SCHEMBL7553666 | 0.71 | ALDH1A1 (0.57) | TSHRTDP1KMT2ANPC1MEN1 | |
| SCHEMBL29709294 | 0.71 | TSHR (0.44) | PRSS1CTSGCTRB1CMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011074141-A1 | PROCESS FOR TREATING KERATIN FIBERS | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |