Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504485 | 1.00 | TSHR (0.50) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL2996805 | 0.92 | TSHR (0.54) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL998239 | 0.90 | TSHR (0.56) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL417437 | 0.81 | TSHR (0.50) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL29709294 | 0.79 | TSHR (0.44) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL28374366 | 0.78 | TSHR (0.52) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL7959384 | 0.78 | TSHR (0.52) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL28678433 | 0.78 | TSHR (0.52) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL24704036 | 0.78 | TSHR (0.56) | TSHRHPGDSRCCES1CES2 | |
| SCHEMBL1603720 | 0.76 | TSHR (0.56) | TSHRHPGDSRCCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050228086-A1 | Selective oxidation of sodium sulfide in kraft cooking liquors | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-10-13 | — | — | US | disclosed |