Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 5/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140280 | 1.00 | GRM1 (0.45) | GRM1MTORRPTORMLST8GFER | |
| SCHEMBL20142669 | 0.89 | MTOR (0.50) | GRM1MTORRPTORMLST8GFER | |
| SCHEMBL20142672 | 0.89 | MTOR (0.50) | GRM1MTORRPTORMLST8GFER | |
| SCHEMBL20141878 | 0.88 | MTOR (0.44) | GRM1MTORRPTORMLST8GFER | |
| SCHEMBL20139885 | 0.88 | MTOR (0.44) | GRM1MTORRPTORMLST8GFER | |
| SCHEMBL20140827 | 0.87 | MTOR (0.51) | MTORRPTORMLST8GFERATM | |
| SCHEMBL20140629 | 0.87 | CHRM2 (0.49) | GRM1MTORRPTORMLST8MAPT | |
| SCHEMBL20140709 | 0.86 | GRM1 (0.50) | GRM1MTORRPTORMLST8CHRM4 | |
| SCHEMBL20142060 | 0.86 | GRM1 (0.50) | GRM1MTORRPTORMLST8CHRM4 | |
| SCHEMBL20140914 | 0.86 | MTOR (0.47) | GRM1MTORRPTORMLST8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |