SCHEMBL2014284

SCHEMBL2014284

CNC(=O)Oc1ccco1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
PGR P06401 1/20 0.42
GAA P10253 1/20 0.42
PTGS1 P23219 1/20 0.42
MAPK1 P28482 1/20 0.42
ACHE P22303 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
KMT2A Q03164 3/20 0.39
PTPN1 P18031 1/20 0.38
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9125805 0.98 MMP1 (0.45) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL7014063 0.82 MMP1 (0.47) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL5948362 0.81 MMP1 (0.46) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL28863937 0.80 KMT2A (0.45) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL3246728 0.78 MMP1 (0.47) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL28778171 0.78 MMP1 (0.54) MMP1MMP9MMP12ALDH1A1CES2
SCHEMBL1884481 0.78
SCHEMBL16196732 0.77 MMP1 (0.53) MMP1MMP9MMP12ALDH1A1HSD17B10
SCHEMBL7024452 0.77 MMP1 (0.53) MMP1MMP9MMP12ALDH1A1HSD17B10
Water SCHEMBL10938023 0.76 MMP1 (0.53) MMP1MMP9MMP12ALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126441-A Damping EVA foaming material for picocell racket 合肥市尚技体育用品有限公司 2024-06-04 CN claimed
CN-109898342-B Preparation method of scratch-resistant synthetic leather based on high-resilience waterborne polyurethane 四川大学 2021-08-27 CN claimed
CN-111936487-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-09 CN disclosed
CN-113710660-B DOT1L degradation agent and application thereof 达纳-法伯癌症研究公司 2024-07-02 CN disclosed
CN-112312909-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-02 CN disclosed
CN-114736219-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-114751920-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-118139851-A Antitumor compounds 法马马有限公司 2024-06-04 CN disclosed
CN-118126441-A Damping EVA foaming material for picocell racket 合肥市尚技体育用品有限公司 2024-06-04 CN disclosed
CN-118076584-A Esters of retinoids and bakuchiol and formulations thereof 康纳根有限公司 2024-05-24 CN disclosed
CN-118055926-A ROCK2 inhibitors and uses thereof 哈佛大学的校长及成员们 2024-05-17 CN disclosed
CN-102159203-A Activation of histone deacetylase 1(HDAC1) protects against DNA damage and increases neuronal survival MASSACHUSETTS INST TECHNOLOGY 2011-08-17 CN disclosed
WO-2011073970-A1 A GASTROINTESTINAL IMPLANT DEVICE VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 WO disclosed
WO-2011073967-A1 A BIOMATERIAL VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 WO disclosed
CN-101932592-A Antineoplastic compound PHARMA MAR SA 2010-12-29 CN disclosed
CN-101547689-A Tetra-substituted NDGA derivatives via ether bonds and carbamate bonds and their synthesis and pharmaceutical use ERIMOS PHARMACEUTICALS LLC (US) 2009-09-30 CN disclosed
CN-101010336-A Peptide antibiotics and process for preparing same BIOSOURCE PHARM INC (US) 2007-08-01 CN disclosed
CN-1039276-C Tablet formulations of pesticides E I DU PONT DT NEMOURS AND CO (US) 1998-07-29 CN disclosed
CN-1039948-A The tablet formulation of agricultural chemicals DU PONT (US) 1990-02-28 CN disclosed
EP-0080046-A1 N-alkoxysulfenylcarbamates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-06-01 EP disclosed