Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948362 | 0.82 | MMP1 (0.46) | MMP1MMP9MMP12HSD17B10CES2 | |
| SCHEMBL2014284 | 0.82 | MMP1 (0.46) | MMP1MMP9MMP12HSD17B10CES2 | |
| Benzene SCHEMBL9125805 | 0.81 | MMP1 (0.45) | MMP1MMP9MMP12HSD17B10CES2 | |
| SCHEMBL16196732 | 0.79 | MMP1 (0.53) | MMP1MMP9MMP12HSD17B10CES2 | |
| SCHEMBL7024452 | 0.79 | MMP1 (0.53) | MMP1MMP9MMP12HSD17B10CES2 | |
| SCHEMBL28863937 | 0.78 | KMT2A (0.45) | MMP1MMP9MMP12HSD17B10KMT2A | |
| SCHEMBL28942302 | 0.78 | MMP1 (0.49) | MMP1MMP9MMP12HSD17B10CES2 | |
| SCHEMBL5166336 | 0.77 | — | — | |
| SCHEMBL1039374 | 0.77 | — | — | |
| SCHEMBL28045868 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272198-A1 | USE OF ORGANOPHOSPHOROUS COMPOUNDS FOR PRODUCING A MEDICAMENT FOR TREATING INFECTIONS | Jomaa Pharmaka GmbH (DE) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001070237-A1 | USE OF ORGANOPHOSPHOROUS COMPOUNDS FOR PRODUCING A MEDICAMENT FOR TREATING INFECTIONS | JOMAA PHARMAKA GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |