Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142448 | 0.89 | GSK3A (0.73) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142461 | 0.87 | MEN1 (0.59) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142298 | 0.84 | GSK3A (0.77) | GSK3AGSK3BCCNA2CDK2NPC1 | |
| SCHEMBL20142401 | 0.84 | GSK3A (0.58) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20141907 | 0.82 | GSK3A (0.54) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142859 | 0.81 | GSK3A (0.47) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142492 | 0.81 | GSK3A (0.57) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142475 | 0.78 | GSK3A (0.48) | GSK3AGSK3BCCNA2CDK2ADORA3 | |
| SCHEMBL20142429 | 0.77 | GSK3A (0.78) | GSK3AGSK3BCCNA2CDK2NPC1 | |
| SCHEMBL20142835 | 0.77 | GSK3A (0.57) | GSK3AGSK3BCCNA2CDK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |