Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142094 | 0.91 | RAB9A (0.50) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142475 | 0.91 | GSK3A (0.48) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142305 | 0.90 | DHODH (0.47) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142510 | 0.90 | ZAP70 (0.55) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142504 | 0.89 | CCNA2 (0.49) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142423 | 0.88 | ADORA3 (0.49) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142448 | 0.88 | GSK3A (0.73) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142440 | 0.86 | GSK3A (0.77) | GSK3AGSK3BCDK5CDK5R1CCNA2 | |
| SCHEMBL20142841 | 0.84 | MAPT (0.63) | GSK3AGSK3BADORA3CDK5CDK5R1 | |
| SCHEMBL20142412 | 0.83 | GSK3A (0.56) | GSK3AGSK3BADORA3CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |