SCHEMBL20142997

SCHEMBL20142997

c1cc2c(o1)CNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13540 0.79
Hydrochloric Acid SCHEMBL8437491 0.78 PNMT (0.43)
Hydrochloric Acid SCHEMBL2720370 0.78 PNMT (0.43)
Hydrochloric Acid SCHEMBL8435409 0.74 PNMT (0.40)
SCHEMBL982394 0.67 HTR2C (0.47)
SCHEMBL1868363 0.66 PNMT (0.43)
SCHEMBL25592899 0.66 HTR2A (0.64)
SCHEMBL6434544 0.66 ALDH1A1 (0.32)
Hydrochloric Acid SCHEMBL2999672 0.65 HTR2C (0.46)
SCHEMBL18576433 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559481-B2 Quinoline derivatives ELANCO ANIMAL HEALTH GMBH (DE) 2026-02-24 US disclosed
US-12435068-B2 Anthelmintic compounds ELANCO ANIMAL HEALTH GMBH (DE) 2025-10-07 US disclosed
US-12391682-B2 Isoquinoline derivatives and their use for the treatment of parasitic infections ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-19 US disclosed
US-20250129094-A1 NEW QUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-24 US disclosed
EP-4003524-B1 ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-09 EP disclosed
EP-3634959-B1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS ELANCO ANIMAL HEALTH GMBH (DE) 2025-02-26 EP disclosed
CN-119409690-A Novel insect repellent compound 拜耳动物保健有限责任公司 2025-02-11 CN disclosed
CN-112074514-B Quinoline derivatives 礼蓝动物保健有限公司 2024-10-29 CN disclosed
WO-2024213752-A1 LONG-TERM PREVENTION AND/OR TREATMENT OF A DISEASE BY SLO-1 INHIBITORS ELANCO ANIMAL HEALTH GMBH (DE) 2024-10-17 WO disclosed
EP-3585791-B1 NEW BICYCLIC PYRAZOLE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2024-10-16 EP disclosed
EP-3643711-A1 NEW ANTHELMINTIC COMPOUNDS Bayer Animal Health GmbH (DE) 2020-04-29 EP disclosed
EP-3634959-A1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS Bayer Animal Health GmbH (DE) 2020-04-15 EP disclosed
EP-3615527-A1 NEW AZAQUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2020-03-04 EP disclosed
CN-110770227-A Novel azaquinoline derivatives 拜耳动物保健有限责任公司 2020-02-07 CN disclosed
WO-2019215182-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2019-11-14 WO disclosed
EP-3538512-A1 NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES Bayer Animal Health GmbH (DE) 2019-09-18 EP disclosed
WO-2019025341-A1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS BAYER ANIMAL HEALTH GMBH (DE) 2019-02-07 WO disclosed
WO-2019002132-A1 NEW AZAQUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2019-01-03 WO disclosed
WO-2018197401-A1 NEW BICYCLIC PYRAZOLE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2018-11-01 WO disclosed
WO-2018087036-A1 NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2018-05-17 WO disclosed