Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | PDXK | O00764 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143334 | 0.93 | HPGD (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL16769248 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5346682 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28085869 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL16769247 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Ginkgotoxin SCHEMBL29462283 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Ginkgotoxin SCHEMBL9127650 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11332813 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Ginkgotoxin SCHEMBL1848430 | 0.78 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL5346680 | 0.78 | KDM4E (0.80) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968684-B2 | Polymer-NSAID conjugate | POLYACTIVA PTY LTD (AU) | 2018-05-15 | — | — | US | disclosed |