Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.47 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285448 | 0.95 | KMT2A (0.57) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL1201154 | 0.90 | ALDH1A1 (0.52) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL28185426 | 0.88 | KDM4E (0.60) | KMT2AMEN1KDM4ERECQLPOLM | |
| SCHEMBL27173083 | 0.86 | MEN1 (0.58) | KMT2AMEN1KDM4ERECQLPOLM | |
| SCHEMBL16756230 | 0.86 | KDM4E (0.75) | KMT2AMEN1KDM4ERECQLPOLM | |
| SCHEMBL4643449 | 0.85 | ALDH1A1 (0.50) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL2762750 | 0.85 | ALDH1A1 (0.50) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL2763300 | 0.84 | PTGDR2 (0.49) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL4644325 | 0.84 | PTGDR2 (0.49) | KMT2AMEN1KDM4ERECQLPTGDR2 | |
| SCHEMBL4642017 | 0.84 | PTGDR2 (0.49) | KMT2AMEN1KDM4ERECQLPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969773-B2 | Polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |