Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.52 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.52 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.52 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143639 | 0.95 | KMT2A (0.63) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL1201154 | 0.89 | ALDH1A1 (0.52) | KMT2AKDM4EMEN1RECQLALOX15 | |
| SCHEMBL1908275 | 0.88 | KDM4E (0.55) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL10407328 | 0.87 | KDM4E (0.68) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL27579253 | 0.87 | KDM4E (0.54) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL4644325 | 0.86 | PTGDR2 (0.49) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL2763300 | 0.86 | PTGDR2 (0.49) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL15548290 | 0.85 | KMT2A (0.66) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL15548035 | 0.85 | KMT2A (0.66) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL15548862 | 0.85 | KMT2A (0.66) | KMT2AKDM4EMEN1RECQLPOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |