Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017389 | 0.90 | HCRTR1 (0.41) | HCRTR1HCRTR2OPRM1OPRK1NPC1 | |
| SCHEMBL2012675 | 0.84 | HCRTR1 (0.57) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2011075 | 0.83 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9AKMT2A | |
| SCHEMBL2014681 | 0.77 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 | |
| SCHEMBL2014812 | 0.77 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 | |
| SCHEMBL2010539 | 0.77 | HCRTR1 (0.63) | HCRTR1HCRTR2P2RX7NPC1RAB9A | |
| SCHEMBL2012798 | 0.77 | HCRTR1 (0.48) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 | |
| SCHEMBL2054334 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 | |
| SCHEMBL2013937 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 | |
| SCHEMBL2051291 | 0.75 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1OPRK1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |