Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856717 | 0.91 | KMT2A (0.76) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL9798517 | 0.87 | MAPT (0.59) | KMT2APRSS1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL4001162 | 0.86 | KMT2A (0.66) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL29842346 | 0.86 | KMT2A (0.66) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL470710 | 0.86 | KMT2A (0.66) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL10260429 | 0.86 | KMT2A (0.66) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL1545288 | 0.85 | KMT2A (0.64) | KMT2AMAOBMEN1PRSS1MAPK1 | |
| SCHEMBL22502336 | 0.85 | THRA (0.64) | KMT2AMAOBMEN1PRSS1TSHR | |
| SCHEMBL10460872 | 0.85 | KMT2A (0.64) | KMT2AMAOBMEN1PRSS1SMN1; SMN2 | |
| SCHEMBL6973871 | 0.85 | KMT2A (0.64) | KMT2AMAOBMEN1PRSS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969692-B2 | Process for preparing quinoline derivatives | EXELIXIS, INC. (US) | 2018-05-15 | — | — | US | disclosed |