Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24057868 | 1.00 | DOT1L (0.34) | DOT1LRIPK1TNK2 | |
| SCHEMBL24158150 | 0.89 | DOT1L (0.33) | DOT1LTNK2 | |
| SCHEMBL20834801 | 0.88 | DOT1L (0.34) | DOT1LRIPK1TNK2 | |
| SCHEMBL24058189 | 0.86 | DOT1L (0.33) | DOT1L | |
| SCHEMBL20882129 | 0.85 | DOT1L (0.33) | DOT1LRIPK1 | |
| SCHEMBL24149121 | 0.84 | DOT1L (0.34) | DOT1L | |
| SCHEMBL20834874 | 0.83 | DOT1L (0.33) | DOT1LRIPK1 | |
| SCHEMBL22355532 | 0.83 | BTN3A1 (0.34) | DOT1LRIPK1 | |
| SCHEMBL24158267 | 0.83 | DOT1L (0.34) | DOT1LRIPK1 | |
| SCHEMBL24148995 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154687-A1 | METHODS FOR TREATING SARS COV-2 INFECTIONS | GILEAD SCIENCES, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| EP-3212174-B1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2018-05-16 | — | — | EP | disclosed |