Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20882171 | 0.91 | DOT1L (0.33) | DOT1L | |
| SCHEMBL24057868 | 0.85 | DOT1L (0.34) | DOT1LRIPK1 | |
| SCHEMBL20144187 | 0.85 | DOT1L (0.34) | DOT1LRIPK1 | |
| SCHEMBL24158150 | 0.74 | DOT1L (0.33) | DOT1L | |
| SCHEMBL20834801 | 0.74 | DOT1L (0.34) | DOT1LRIPK1 | |
| SCHEMBL24699947 | 0.74 | BTN3A1 (0.34) | DOT1LRIPK1 | |
| SCHEMBL24700006 | 0.74 | BTN3A1 (0.34) | DOT1LRIPK1 | |
| SCHEMBL24058189 | 0.72 | DOT1L (0.33) | DOT1L | |
| SCHEMBL21116657 | 0.72 | BCHE (0.47) | — | |
| SCHEMBL23992605 | 0.69 | HINT1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150608-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-04-10 | — | — | EP | disclosed |