Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621122 | 0.87 | CYP2C19 (0.72) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL13060934 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL13006889 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL10285704 | 0.85 | KDM4E (0.57) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL24334501 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL13746185 | 0.80 | CYP2C19 (0.62) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL23928125 | 0.79 | POLB (0.52) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL11769350 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL20160095 | 0.77 | CYP2C19 (0.59) | ALDH1A1HPGDCYP2C19TSHRMEN1 | |
| SCHEMBL17285877 | 0.77 | TMEM97 (0.47) | MEN1KMT2AKDM4EF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220178934-A1 | SIGNALING CONJUGATES AND METHODS OF USE | VENTANA MED SYST INC (US) | 2022-06-09 | — | — | US | disclosed |
| EP-3764084-A1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | Ventana Medical Systems, Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3764083-A1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | Ventana Medical Systems, Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-2972227-B1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | VENTANA MED SYST INC (US) | 2020-05-06 | — | — | EP | disclosed |
| EP-2831587-B1 | SIGNALING CONJUGATES AND METHODS OF USE | VENTANA MED SYST INC (US) | 2018-05-16 | — | — | EP | disclosed |