SCHEMBL20160095

SCHEMBL20160095

CN1CCC(C(=O)NCCCCCc2ccccc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.59
ASAH1 Q13510 1/20 0.56
ALDH1A1 P00352 3/20 0.55
TSHR P16473 2/20 0.55
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KDM4E B2RXH2 1/20 0.55
MAPT P10636 2/20 0.54
HPGD P15428 1/20 0.54
POLB P06746 2/20 0.54
KMT2A Q03164 2/20 0.53
FKBP1A P62942 2/20 0.53
MEN1 O00255 1/20 0.53
NAMPT P43490 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13746185 0.95 CYP2C19 (0.62) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL13621122 0.89 CYP2C19 (0.72) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL21569633 0.86 CYP2C19 (0.56) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL26110422 0.83 KMT2A (0.56) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL26109813 0.83 KMT2A (0.56) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL28499155 0.82 MTNR1A (0.61) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL21569748 0.81 CYP2C19 (0.58) CYP2C19ALDH1A1TSHRGAAL3MBTL1
SCHEMBL13746186 0.81 NPSR1 (0.72) ALDH1A1TSHRMAPTHPGDPOLB
SCHEMBL21045499 0.79 ALDH1A1 (0.48) CYP2C19ALDH1A1TSHRGAAKDM4E
SCHEMBL29411602 0.79 ALDH1A1 (0.48) CYP2C19ALDH1A1TSHRGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089695-A1 TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USE DYNAVAX TECHNOLOGIES CORPORATION (US) 2018-05-17 WO disclosed