Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709963 | 0.89 | TP53 (0.41) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL24709967 | 0.88 | TP53 (0.40) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL19245438 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL20144578 | 0.84 | TP53 (0.37) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL23919438 | 0.83 | MEN1 (0.45) | KMT2A | |
| SCHEMBL24489332 | 0.79 | MEN1 (0.41) | HPGDALDH1A1KMT2APSMB5CNR1 | |
| SCHEMBL19776870 | 0.79 | TP53 (0.34) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL22548790 | 0.79 | TP53 (0.38) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL24913317 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL13629818 | 0.77 | CASP2 (0.47) | SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321279-A1 | EXENATIDE MODIFIER AND USE THEREOF | Bright Gene Bio-Medical Technology Co., Ltd. (CN) | 2018-05-16 | — | — | EP | disclosed |