Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 7/20 | 0.60 |
| ▸ | MMP9 | P14780 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | MMP14 | P50281 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813094 | 0.86 | CDK1 (0.62) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL2015833 | 0.83 | KDM4E (0.53) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL2013981 | 0.83 | HTT (0.46) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL10414290 | 0.81 | CDK1 (0.67) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL10415547 | 0.81 | MAPT (0.66) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11663296 | 0.79 | MAPT (0.64) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL2014951 | 0.79 | MEN1 (0.49) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| Chloroxine SCHEMBL9135479 | 0.78 | KDM4E (0.96) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| Chloroxine SCHEMBL22734873 | 0.78 | KDM4E (0.96) | CDK1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL11955299 | 0.78 | CDK1 (0.74) | CDK1L3MBTL1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |