SCHEMBL20144645

SCHEMBL20144645

Cc1cc(/C=C/C=C/c2cc(Cl)c(Cl)c(Cl)c2)cc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.38
PTGS1 P23219 7/20 0.37
PTGS2 P35354 7/20 0.37
ALOX5 P09917 3/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 4/20 0.34
CHRM1 P11229 1/20 0.34
ALOX15 P16050 1/20 0.34
MAOA P21397 1/20 0.34
TBXA2R P21731 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
SIRT1 Q96EB6 1/20 0.32
HPGD P15428 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TTR P02766 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2622604 0.86 ALDH1A1 (0.45) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL23464454 0.76 ALDH1A1 (0.46) RAPGEF4ALDH1A1CYP3A4CHRM1ALOX15
SCHEMBL25852175 0.76 CYP3A4 (0.36) RAPGEF4PTGS1PTGS2ALOX5ALDH1A1
SCHEMBL11039433 0.73 ALDH1A1 (0.44) ALOX5ALDH1A1CYP3A4HPGDCRHBP
SCHEMBL15128427 0.72 ALDH1A1 (0.33) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL18143743 0.72 TUBB1 (0.67) PTGS1PTGS2ALOX5TTRCYP1A2
SCHEMBL18143739 0.72 TUBB1 (0.67) PTGS1PTGS2ALOX5TTRCYP1A2
SCHEMBL21021185 0.72 PTGS1 (0.63) PTGS1PTGS2ALOX5MAOATTR
SCHEMBL21021677 0.71 PTGS1 (0.30) PTGS1PTGS2ALOX5
SCHEMBL16313428 0.71 ALDH1A1 (0.34) ALDH1A1CYP3A4HPGDCRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102708-B1 CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME FUJIFILM CORP (JP) 2018-05-16 EP disclosed