Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375737 | 0.88 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL25139692 | 0.88 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL29178408 | 0.86 | CTSK (0.45) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL30047908 | 0.86 | CTSK (0.45) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL17884307 | 0.83 | CTSK (0.54) | NFKB1NFKB2RELACTSKCTSS | |
| SCHEMBL16330414 | 0.83 | CTSK (0.54) | NFKB1NFKB2RELACTSKCTSS | |
| SCHEMBL6885122 | 0.81 | HDAC4 (0.41) | NFKB1NFKB2RELACTSKCTSS | |
| SCHEMBL28690504 | 0.80 | CTSK (0.48) | NFKB1NFKB2RELACTSKCTSS | |
| SCHEMBL28690502 | 0.80 | CTSK (0.48) | NFKB1NFKB2RELACTSKCTSS | |
| SCHEMBL17880416 | 0.78 | CTSK (0.49) | NFKB1NFKB2RELACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751124-B1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |