Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047908 | 1.00 | CTSK (0.45) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL25139692 | 0.87 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL375737 | 0.87 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL20144682 | 0.86 | NFKB1 (0.44) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL29178395 | 0.79 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL29178398 | 0.79 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL24815288 | 0.79 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL24812376 | 0.76 | CTSK (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL29178308 | 0.76 | CTSK (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25139652 | 0.74 | HDAC4 (0.56) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |