SCHEMBL20144683

SCHEMBL20144683

Cc1nc(C(F)F)c(N)s1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17045369 0.79 SMN1; SMN2 (0.31) SMN1; SMN2NOS1
SCHEMBL9967993 0.76 NPC1 (0.30) SMN1; SMN2
SCHEMBL16661429 0.71
SCHEMBL802240 0.70 KMT2A (0.34)
SCHEMBL10119505 0.70 GRM5 (0.33)
SCHEMBL5608462 0.68
SCHEMBL2616828 0.67
SCHEMBL20808750 0.67
SCHEMBL918550 0.66 MAPT (0.33)
SCHEMBL20008624 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3013803-B1 N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-05-16 EP disclosed