Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868029 | 0.81 | — | — | |
| SCHEMBL18427073 | 0.81 | — | — | |
| SCHEMBL15113133 | 0.81 | KMT2A (0.35) | KMT2A | |
| SCHEMBL9967993 | 0.73 | NPC1 (0.30) | — | |
| SCHEMBL21720478 | 0.71 | KMT2A (0.38) | KMT2A | |
| SCHEMBL2732554 | 0.70 | KMT2A (0.56) | KMT2A | |
| SCHEMBL20144683 | 0.70 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL12138136 | 0.69 | KMT2A (0.39) | KMT2A | |
| SCHEMBL16661429 | 0.68 | — | — | |
| SCHEMBL802242 | 0.68 | COMT (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556205-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9556205-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9545105-B2 | 1-(heterocyclic carbonyl) piperidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-17 | — | — | US | disclosed |
| US-9320277-B2 | Fungicide N-cycloalkyl-N-biphenylmethyl-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-8927581-B2 | Fungicidal N-(2-pyridylpropyl) carboxamide derivatives and their oxa, aza and thia analogues | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8841332-B2 | Fungicidal N-(2-phenoxyethyl)carboxamide derivatives and their aza, thia and sila analogues | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20140171474-A1 | FUNGICIDE N-CYCLOALKYL-N-BIPHENYLMETHYL-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH | 2014-06-19 | — | — | US | disclosed |
| US-8680127-B2 | Fungicide N-cycloalkyl-N-biphenylmethyl-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20130261158-A1 | FUNGICIDAL N-(2-PHENOXYETHYL)CARBOXAMIDE DERIVATIVES AND THEIR AZA, THIA AND SILA ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261155-A1 | 1-(HETEROCYCLIC CARBONYL) PIPERIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8026195-B2 | Fungicidal N-cycloalkyl-carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-27 | — | — | US | disclosed |
| US-8026195-B2 | Fungicidal N-cycloalkyl-carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-27 | — | — | US | disclosed |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20090326016-A1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090326016-A1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261155-A1 | 1-(HETEROCYCLIC CARBONYL) PIPERIDINES | CBR3, CBR1, CYP51A1 | KMT2A 2364/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | KMT2A 817/4885 |
| US-20140171474-A1 | FUNGICIDE N-CYCLOALKYL-N-BIPHENYLMETHYL-CARBOXAMIDE DERIVATIVES | CNPY2, CBR3, CYP51A1 | KMT2A 421/4885 |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | PNPO, AZI2, CYP51A1 | KMT2A 769/4885 |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | CYP51A1, ME2, ME3 | KMT2A 235/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | KMT2A 2498/4885 |
| US-20090326016-A1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | CBR3, CBR1, CYCS | KMT2A 1313/4885 |
| US-20130261158-A1 | FUNGICIDAL N-(2-PHENOXYETHYL)CARBOXAMIDE DERIVATIVES AND THEIR AZA, THIA AND SILA ANALOGUES | CYP51A1, TET3, CIP2A | KMT2A 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.