Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903701 | 0.83 | GAA (0.37) | MAPTALDH1A1POLBRECQLRAB9A | |
| SCHEMBL2062185 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1POLBRECQLRAB9A | |
| SCHEMBL3669891 | 0.83 | IKBKB (0.36) | MAPTALDH1A1POLBRECQLRAB9A | |
| SCHEMBL13478968 | 0.79 | L3MBTL1 (0.38) | MAPTALDH1A1CNR1POLBRECQL | |
| SCHEMBL13980907 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1CNR1POLBRECQL | |
| SCHEMBL12057434 | 0.75 | CHRM4 (0.39) | MAPTALDH1A1CNR1POLBRECQL | |
| SCHEMBL3344131 | 0.74 | CNR1 (0.47) | MAPTALDH1A1CNR1RECQLRAB9A | |
| SCHEMBL9289574 | 0.71 | ALDH1A1 (0.45) | MAPTALDH1A1POLBRAB9AHPGD | |
| SCHEMBL2199155 | 0.70 | MAPT (0.56) | MAPTALDH1A1CNR1POLBRECQL | |
| SCHEMBL2566875 | 0.69 | KMT2A (0.32) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380767-A | Thiazole amide compound containing diphenylamino group and preparation method and application thereof | 安徽理工大学 | 2022-04-22 | — | — | CN | claimed |
| CN-120004819-A | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119101010-A | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-114560826-B | Thiazole amide compound containing diphenyl ether group and preparation method and application thereof | 安徽理工大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-114560826-A | Diphenyl ether group-containing thiazole amide compound and preparation method and application thereof | 安徽理工大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114380767-A | Thiazole amide compound containing diphenylamino group and preparation method and application thereof | 安徽理工大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-111788200-A | Imide derivative and fungicide comprising the same as active ingredient | 北兴化学工业株式会社 | 2020-10-16 | — | — | CN | disclosed |
| US-8541406-B2 | Thiadiazole derivatives for the treatment of neurodegenerative diseases | NV REMYND (BE) | 2013-09-24 | — | — | US | disclosed |
| EP-1572663-B1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
| EP-1474407-A1 | DIFLUOROMETHYL THIAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004054982-A1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004039789-A1 | THIAZOL-(BI)CYCLOALKYL-CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | WO | disclosed |
| WO-2004035555-A1 | THIAZOLYL BIPHENYL AMIDES | BAYER CROPSCIENCE AG (DE) | 2004-04-29 | — | — | WO | disclosed |
| WO-2003066610-A1 | DIFLUOROMETHYL THIAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
| EP-0824099-B1 | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI CHEMICALS INC (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-5965774-A | CONTROLLING PLANT DISEASES AGAINST BOTRYTIS CINEREA, POWDERY MILDEW, PYRICULARIA ORYZAE OF RICE PLANT | MITSUI CHEMICALS, INC. (JP) | 1999-10-12 | — | — | US | disclosed |
| US-5914344-A | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI CHEMICALS, INC. (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0824099-A1 | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | MRPL21, FOXM1, FLT3 | MAPT 3557/4885ALDH1A1 269/4885CNR1 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.