Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MAN2A1 | Q16706 | 3/20 | 0.44 |
| ▸ | MAN1B1 | Q9UKM7 | 3/20 | 0.44 |
| ▸ | MAN2B1 | O00754 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144687 | 0.85 | GAA (0.56) | MGAMSIKCNQ3KCNQ2GAA | |
| SCHEMBL8400412 | 0.84 | HTR1D (0.43) | SOS1HTR1BSLC6A2HTR2ASLC6A4 | |
| SCHEMBL20144711 | 0.83 | GAA (0.54) | MGAMSIKCNQ3KCNQ2GAA | |
| SCHEMBL6030479 | 0.78 | SOS1 (0.56) | SOS1GAAL3MBTL1HTR1BKDM1A | |
| Bromide SCHEMBL7978275 | 0.76 | SOS1 (0.54) | SOS1GAAL3MBTL1HTR1BKDM1A | |
| Hydrochloric Acid SCHEMBL6984774 | 0.76 | SOS1 (0.54) | SOS1GAAL3MBTL1HTR1BKDM1A | |
| Bromide SCHEMBL7978277 | 0.76 | SOS1 (0.54) | SOS1GAAL3MBTL1HTR1BKDM1A | |
| SCHEMBL2092719 | 0.75 | MGAM (0.43) | MGAMSIMAN2A1MAN1B1MAN2B1 | |
| SCHEMBL2093243 | 0.75 | MGAM (0.43) | MGAMSIMAN2A1MAN1B1MAN2B1 | |
| SCHEMBL27747201 | 0.75 | SOS1 (0.41) | SOS1RIPK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025374-A | Azetidine, pyrrolidine and piperidine derivatives as 5HT1 receptor agonists | MERCK SHARP & DOHME, LTD. (GB) | 2000-02-15 | — | — | US | disclosed |