Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.75 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.75 |
| ▸ | CTH | P32929 | 1/20 | 0.71 |
| ▸ | AKT1 | P31749 | 4/20 | 0.57 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nanafrocin SCHEMBL2111571 | 0.86 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| Nanaomycin SCHEMBL18567076 | 0.86 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| Nanaomycin SCHEMBL30778402 | 0.86 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| Nanaomycin SCHEMBL20473784 | 0.86 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| Nanaomycin SCHEMBL30861963 | 0.86 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| SCHEMBL28398864 | 0.77 | DNMT3B (0.77) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| SCHEMBL30193239 | 0.76 | DNMT3B (0.82) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| SCHEMBL29927569 | 0.74 | DNMT3B (0.78) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| SCHEMBL1177648 | 0.73 | DNMT3B (0.66) | DNMT3BHSP90AA1PAX8CTHAKT1 | |
| SCHEMBL20442857 | 0.73 | DNMT3B (0.66) | DNMT3BHSP90AA1PAX8CTHAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321371-A1 | NOVEL METHODS FOR RAPID DRUG SUSCEPTIBILITY TESTING AND DRUG SCREENS FOR GROWING AND NON-GROWING CELLS OF PROKARYOTIC AND EUKARYOTIC ORIGIN | Zhang, Ying (US) | 2018-05-16 | — | — | EP | disclosed |