Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.82 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.82 |
| ▸ | AKT1 | P31749 | 3/20 | 0.61 |
| ▸ | CTH | P32929 | 1/20 | 0.61 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | TCF4 | P15884 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | STAT3 | P40763 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nanaomycin SCHEMBL30778402 | 0.90 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| Nanaomycin SCHEMBL20473784 | 0.90 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| Nanaomycin SCHEMBL30861963 | 0.90 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| Nanaomycin SCHEMBL18567076 | 0.90 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| Nanafrocin SCHEMBL2111571 | 0.90 | HSP90AA1 (1.00) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| SCHEMBL29927569 | 0.87 | DNMT3B (0.78) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| SCHEMBL28398864 | 0.76 | DNMT3B (0.77) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| SCHEMBL20144857 | 0.76 | DNMT3B (0.75) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| SCHEMBL20442857 | 0.70 | DNMT3B (0.66) | DNMT3BHSP90AA1PAX8AKT1CTH | |
| SCHEMBL1177648 | 0.70 | DNMT3B (0.66) | DNMT3BHSP90AA1PAX8AKT1CTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109694-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12551555-B2 | Compositions and methods for potentiating immune activity | KUMQUAT BIOSCIENCES INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-12503464-B2 | 1,2,5-thiadiazolidin-3-one 1,1-dioxide containing compounds and uses thereof | KUMQUAT BIOSCIENCES INC. (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250304570-A1 | BENZO-FUSED N-HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC (US) | 2025-10-02 | — | — | US | disclosed |
| US-20250296927-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2025-09-25 | — | — | US | disclosed |
| US-20240398828-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-12-05 | — | — | US | disclosed |
| US-20240166641-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-05-23 | — | — | US | disclosed |
| US-20230092294-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE RESPONSE | KUMQUAT BIOSCIENCES INC. | 2023-03-23 | — | — | US | disclosed |
| US-20230044323-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | KUMQUAT BIOSCIENCES INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230092294-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE RESPONSE | MYD88, NFATC1, ICOS | DNMT3B 793/4885HSP90AA1 1636/4885PAX8 1121/4885 |
| US-20260109694-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CCR10, SLC11A2, MSR1 | DNMT3B 4276/4885HSP90AA1 3511/4885PAX8 4714/4885 |
| US-12551555-B2 | Compositions and methods for potentiating immune activity | PTPRCAP, PTPN2, PTPRC | DNMT3B 1976/4885HSP90AA1 3576/4885PAX8 1757/4885 |
| US-20230044323-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | NFATC1, MYD88, ICOS | DNMT3B 710/4885HSP90AA1 1700/4885PAX8 909/4885 |
| US-12503464-B2 | 1,2,5-thiadiazolidin-3-one 1,1-dioxide containing compounds and uses thereof | BRCA1, STING1, IFNG | DNMT3B 2913/4885HSP90AA1 653/4885PAX8 3526/4885 |
| US-20240398828-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | CD74, HLA-DRB1, CD47 | DNMT3B 2954/4885HSP90AA1 2735/4885PAX8 4038/4885 |
| US-20250304570-A1 | BENZO-FUSED N-HETEROCYCLES AND USES THEREOF | NFATC1, BRCA1, MYD88 | DNMT3B 4329/4885HSP90AA1 1138/4885PAX8 3394/4885 |
| US-20250296927-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | MYD88, TP53, NFATC1 | DNMT3B 4621/4885HSP90AA1 2695/4885PAX8 3909/4885 |
| US-20240166641-A1 | HETEROCYCLES AND USES THEREOF | KRAS, HRAS, TP53 | DNMT3B 4114/4885HSP90AA1 1487/4885PAX8 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.