Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144974 | 0.77 | HCRTR1 (0.70) | HCRTR2HCRTR1KMT2A | |
| SCHEMBL20145031 | 0.77 | HCRTR2 (0.70) | HCRTR2HCRTR1 | |
| SCHEMBL20144824 | 0.77 | HCRTR2 (0.70) | HCRTR2HCRTR1 | |
| SCHEMBL20144768 | 0.77 | HCRTR1 (0.70) | HCRTR2HCRTR1 | |
| SCHEMBL15631350 | 0.74 | GUCY1B2 (0.51) | — | |
| SCHEMBL20145268 | 0.73 | HCRTR1 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL13735649 | 0.73 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL5909199 | 0.73 | ALDH1A1 (0.64) | KMT2A | |
| SCHEMBL6265337 | 0.73 | ALDH1A1 (0.64) | KMT2A | |
| SCHEMBL263251 | 0.70 | HCRTR2 (0.50) | HCRTR2HCRTR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |