Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 5/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CCNK | O75909 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144869 | 0.82 | IL1B (0.55) | CCR6DPP4CCNKCCNA2CDK2 | |
| SCHEMBL20145261 | 0.82 | IL1B (0.55) | CCR6DPP4CCNKCCNA2CDK2 | |
| SCHEMBL20145167 | 0.81 | CCNK (0.48) | CCR6DPP4HCRTR1CCNKCDK12 | |
| SCHEMBL31308025 | 0.81 | CCR6 (0.51) | CCR6DPP4HCRTR1CCNKCCNA2 | |
| SCHEMBL15739705 | 0.80 | HCRTR1 (0.55) | CCR6DPP4HCRTR1CCNKCCNA2 | |
| SCHEMBL18607634 | 0.80 | CCR6 (0.55) | CCR6DPP4HCRTR1CCNKCCNA2 | |
| SCHEMBL30955917 | 0.77 | CCNK (0.47) | CCR6HCRTR1CCNKCDK2CDK12 | |
| SCHEMBL15739645 | 0.77 | CCR6 (0.61) | CCR6DPP4HCRTR1 | |
| SCHEMBL16032596 | 0.75 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL16730436 | 0.74 | CCR6 (0.58) | CCR6DPP4CCNKCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |