Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828298 | 0.91 | CHRNB2 (0.47) | CHRNB2CHRNA4MKNK1DGAT1 | |
| SCHEMBL10078051 | 0.84 | SLC6A4 (0.43) | DGAT1 | |
| SCHEMBL30314525 | 0.84 | SLC6A4 (0.43) | DGAT1 | |
| Hydrochloric Acid SCHEMBL517567 | 0.83 | SLC6A4 (0.42) | DGAT1 | |
| Hydrochloric Acid SCHEMBL31347800 | 0.83 | SLC6A4 (0.42) | DGAT1 | |
| SCHEMBL1928105 | 0.82 | DGAT1 (0.47) | KCNH2DGAT1 | |
| SCHEMBL4000064 | 0.82 | DGAT1 (0.47) | KCNH2DGAT1 | |
| SCHEMBL30296157 | 0.82 | DGAT1 (0.47) | KCNH2DGAT1 | |
| SCHEMBL28671509 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4ROCK1ROCK2KCNH2 | |
| SCHEMBL29517983 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4ROCK1ROCK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |