Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006029 | 1.00 | GBA1 (0.36) | GBA1IDO1TDO2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL31226763 | 0.98 | IDO1 (0.39) | GBA1IDO1TDO2CHRNB4CHRNA3 | |
| SCHEMBL1728961 | 0.84 | IDO1 (0.42) | GBA1IDO1TDO2ADRB2PDE2A | |
| SCHEMBL557913 | 0.84 | IDO1 (0.42) | GBA1IDO1TDO2ADRB2PDE2A | |
| SCHEMBL4826929 | 0.84 | ADRB2 (0.39) | IDO1TDO2ADRB2GABRA1GABRB1 | |
| SCHEMBL4837352 | 0.84 | ADRB2 (0.39) | IDO1TDO2ADRB2GABRA1GABRB1 | |
| SCHEMBL1004099 | 0.84 | IDO1 (0.42) | GBA1IDO1TDO2ADRB2PDE2A | |
| SCHEMBL4826922 | 0.84 | ADRB2 (0.39) | IDO1TDO2ADRB2GABRA1GABRB1 | |
| SCHEMBL12263051 | 0.82 | GABRA1 (0.38) | IDO1TDO2CHRNB4CHRNA3GABRA1 | |
| Hydrochloric Acid SCHEMBL1876903 | 0.81 | IDO1 (0.45) | GBA1IDO1TDO2ADRB2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |