Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | LPL | P06858 | 3/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722016 | 0.87 | TSHR (0.41) | JAK2BTKLIPGLPLP4HB | |
| SCHEMBL16034519 | 0.86 | JAK2 (0.40) | JAK2BTKLIPGLPLP4HB | |
| SCHEMBL2029210 | 0.86 | JAK2 (0.39) | JAK2BTKLIPGLPLP4HB | |
| SCHEMBL29691116 | 0.85 | LIPG (0.41) | LIPGLPLP4HBCXCR2LIPE | |
| SCHEMBL18865621 | 0.85 | LIPG (0.41) | LIPGLPLP4HBCXCR2LIPE | |
| Lithium Ion SCHEMBL31224653 | 0.84 | JAK2 (0.40) | JAK2BTKLIPGLPLP4HB | |
| SCHEMBL562324 | 0.83 | LMNA (0.40) | JAK2BTKUCHL1 | |
| SCHEMBL5840924 | 0.83 | NPC1 (0.42) | JAK2BTKUCHL1CA1CA2 | |
| SCHEMBL17442251 | 0.83 | KDM4E (0.37) | JAK2BTKLIPGLPLP4HB | |
| SCHEMBL12215764 | 0.81 | TSHR (0.50) | UCHL1CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |