Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035409 | 0.94 | KMT2A (0.36) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL16035002 | 0.79 | HDAC3 (0.38) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL8526820 | 0.76 | KMT2A (0.44) | KDM4EALDH1A1USP2KMT2AMAPT | |
| SCHEMBL16035156 | 0.74 | MEN1 (0.40) | KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL9733862 | 0.74 | HSD17B10 (0.37) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL19512251 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL17559391 | 0.70 | KMT2A (0.44) | ALDH1A1USP2TDP1KMT2AMAPT | |
| SCHEMBL587574 | 0.69 | KMT2A (0.44) | KDM4EALDH1A1USP2KMT2AMAPT | |
| SCHEMBL9304224 | 0.68 | MAPT (0.51) | KDM4EALDH1A1USP2KMT2AMAPT | |
| SCHEMBL27835926 | 0.66 | L3MBTL1 (0.36) | KDM4EALDH1A1USP2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |