Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965608 | 0.74 | PRSS1 (0.59) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL10419257 | 0.72 | TPMT (0.46) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL21792281 | 0.72 | PRSS1 (1.00) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL10991644 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HPGDACHECNR2MEN1 | |
| SCHEMBL17424935 | 0.72 | TPMT (0.46) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL347092 | 0.72 | TPMT (0.59) | PRSS1PRSS2C1SPRSS3TPMT | |
| Hydrochloric Acid SCHEMBL29174232 | 0.70 | PRSS1 (0.95) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL28417343 | 0.69 | TPMT (0.55) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL4047000 | 0.69 | TPMT (0.42) | PRSS1PRSS2C1SPRSS3TPMT | |
| SCHEMBL4046998 | 0.69 | TPMT (0.42) | PRSS1PRSS2C1SPRSS3TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |