Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129522 | 0.85 | GCGR (0.57) | GCGRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL10129495 | 0.84 | GCGR (0.43) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL20146246 | 0.84 | GCGR (0.43) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL10129253 | 0.81 | GCGR (0.45) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL10129544 | 0.79 | KDM5B (0.41) | GCGRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL10129494 | 0.79 | GCGR (0.46) | GCGRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL10434301 | 0.79 | GCGR (0.41) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL10129501 | 0.78 | HMGCR (0.38) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL10129934 | 0.78 | GCGR (0.38) | GCGRAKT1ALDH1A1CYP3A4PDE6D | |
| SCHEMBL14045937 | 0.75 | GCGR (0.54) | GCGRALDH1A1CYP3A4PDE6DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247739-B1 | ((2S,4R)-4,6-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YL)METHYL CARBOXYLATE AND PROCESS FOR ITS PRODUCTION EMPLOYING A 2-DEOXYRIBOSE-5-PHOSPHATE ALDOLASE (DERA) | LEK PHARMACEUTICALS (SI) | 2018-05-16 | — | — | EP | disclosed |