Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014629 | 1.00 | STAT3 (0.38) | STAT3PPARGMEN1KMT2ASLC1A3 | |
| SCHEMBL9306403 | 0.85 | KDM4E (0.44) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL3064836 | 0.81 | SMN1; SMN2 (0.43) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL7265141 | 0.81 | SMN1; SMN2 (0.43) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL1990107 | 0.81 | SMN1; SMN2 (0.43) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL10572149 | 0.78 | CA12 (0.44) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL10808505 | 0.78 | CA2 (0.40) | STAT3PPARGMEN1KMT2ASLC1A3 | |
| SCHEMBL2325751 | 0.78 | CA12 (0.44) | STAT3PPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL12622492 | 0.77 | KMT2A (0.37) | STAT3MEN1KMT2AALDH1A1RECQL | |
| SCHEMBL11542141 | 0.77 | SLC1A3 (0.42) | STAT3PPARGMEN1KMT2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338892-A1 | Prostate specific membrane antigen inhibitors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-06-29 | — | — | EP | disclosed |