Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265141 | 0.86 | SMN1; SMN2 (0.43) | PPARGKEAP1NFE2L2STAT3SLC1A3 | |
| SCHEMBL1990107 | 0.86 | SMN1; SMN2 (0.43) | PPARGKEAP1NFE2L2STAT3SLC1A3 | |
| SCHEMBL3064836 | 0.86 | SMN1; SMN2 (0.43) | PPARGKEAP1NFE2L2STAT3SLC1A3 | |
| SCHEMBL2014629 | 0.85 | STAT3 (0.38) | KDM4EPPARGKEAP1NFE2L2STAT3 | |
| SCHEMBL2014631 | 0.85 | STAT3 (0.38) | KDM4EPPARGKEAP1NFE2L2STAT3 | |
| SCHEMBL13369726 | 0.85 | KMT2A (0.41) | PPARGKEAP1NFE2L2STAT3SLC1A3 | |
| SCHEMBL2325751 | 0.83 | CA12 (0.44) | PPARGSTAT3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10808505 | 0.83 | CA2 (0.40) | PPARGSTAT3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10572149 | 0.83 | CA12 (0.44) | PPARGSTAT3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10465481 | 0.83 | KDM4E (0.48) | KDM4EPPARGKEAP1NFE2L2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |