Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146465 | 0.90 | HTR2C (0.43) | L3MBTL1HTR2CBCHEACHEPDK1 | |
| SCHEMBL20146359 | 0.84 | ALDH1A1 (0.41) | L3MBTL1HTR2CALDH1A1LMNAGAA | |
| SCHEMBL20146348 | 0.80 | HTR2C (0.43) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL20146478 | 0.79 | L3MBTL1 (0.44) | L3MBTL1HTR2CALDH1A1LMNAGAA | |
| SCHEMBL20146469 | 0.78 | HTR2C (0.45) | L3MBTL1HTR2CLMNAPDK1PDK2 | |
| SCHEMBL20146354 | 0.77 | HTR2C (0.41) | L3MBTL1HTR2CBCHEPDK1PDK2 | |
| SCHEMBL20146366 | 0.72 | HTR2C (0.49) | L3MBTL1HTR2CALDH1A1GAAPDK1 | |
| SCHEMBL21538569 | 0.72 | SMN1; SMN2 (0.44) | L3MBTL1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL20146330 | 0.71 | HTR2C (0.48) | HTR2CALDH1A1LMNANPC1RAB9A | |
| SCHEMBL20146368 | 0.71 | HTR2C (0.44) | L3MBTL1HTR2CALDH1A1GAAPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321271-A1 | METHOD FOR PRODUCING 7H-PYRROLO[2, 3-D]PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | Japan Tobacco, Inc. (JP) | 2018-05-16 | — | — | EP | disclosed |