Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | GNA15 | P30679 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129584 | 0.91 | THRB (0.60) | THRBFFAR1FFAR4HCAR2AKR1B10 | |
| SCHEMBL16768511 | 0.90 | THRB (0.58) | THRBFFAR1FFAR4HCAR2GNA15 | |
| SCHEMBL16768513 | 0.90 | THRB (0.58) | THRBFFAR1FFAR4HCAR2GNA15 | |
| SCHEMBL16768510 | 0.90 | THRB (0.58) | THRBFFAR1FFAR4HCAR2GNA15 | |
| SCHEMBL22129615 | 0.87 | THRB (0.65) | THRBFFAR1FFAR4HCAR2AKR1B10 | |
| SCHEMBL16755603 | 0.87 | THRB (0.65) | THRBFFAR1FFAR4HCAR2AKR1B10 | |
| SCHEMBL149640 | 0.87 | THRB (0.59) | THRBHCAR2TDP1AKR1B10AKR1B1 | |
| SCHEMBL25247933 | 0.82 | THRB (0.56) | THRBFFAR1AKR1B10AKR1B1 | |
| SCHEMBL17914469 | 0.81 | TSHR (0.53) | THRBHCAR2AKR1B10AKR1B1APP | |
| SCHEMBL40718 | 0.81 | THRB (0.67) | THRBHCAR2TDP1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077016-B1 | SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |