Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914469 | 0.93 | TSHR (0.53) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL40718 | 0.93 | THRB (0.67) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL27759950 | 0.91 | THRB (0.56) | THRBHCAR2AKR1B10AKR1B1HSD17B10 | |
| Ethylene Glycol SCHEMBL6491859 | 0.89 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Carbon Monoxide SCHEMBL10707595 | 0.89 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL13777519 | 0.88 | THRB (0.48) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL9806249 | 0.88 | TSHR (0.59) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL144847 | 0.87 | THRB (0.59) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL31453304 | 0.87 | HCAR2 (0.59) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL20146602 | 0.87 | THRB (0.53) | THRBHCAR2AKR1B10AKR1B1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| US-11618823-B2 | High refractive index siloxane insert materials for embedded contact lenses | ALCON INC. (CH) | 2023-04-04 | — | — | US | claimed |
| EP-4121802-A1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| US-7790824-B2 | High refractive index ophthalmic device materials | ALCON, INC. (CH) | 2010-09-07 | — | — | US | claimed |
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS | 2009-09-17 | — | — | US | claimed |
| EP-1080382-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2009-07-08 | — | — | EP | claimed |
| US-20090043006-A1 | High Refractive Index Ophthalmic Device Materials | ALCON, INC. (CH) | 2009-02-12 | — | — | US | claimed |
| WO-2009015256-A2 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON, INC. (CH) | 2009-01-29 | — | — | WO | claimed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | claimed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | claimed |
| US-6353069-B1 | INTRAOCULAR LENSES THAT HAVE HIGH REFRACTIVE INDEXES, ARE FLEXIBLE AND TRANSPARENT, CAN BE INSERTED INTO EYE THROUGH RELATIVELY SMALL INCISION, RECOVER ORIGINAL SHAPE AFTER HAVING BEEN INSERTED, AND ARE FREE OF GLISTENINGS | ALCON MANUFACTURING, LTD. | 2002-03-05 | — | — | US | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | PPIH, ARG1, P4HA1 | THRB 3915/4885HCAR2 257/4885AKR1B10 3169/4885 |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | THRB 2506/4885HCAR2 3782/4885AKR1B10 3460/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | THRB 4655/4885HCAR2 2093/4885AKR1B10 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.