Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 2/20 | 0.32 |
| ▸ | HEXB | P07686 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16390153 | 0.85 | PSMB5 (0.47) | KMT2AMEN1L3MBTL1PSMB5NOS3 | |
| SCHEMBL8286283 | 0.73 | MAPK1 (0.40) | KMT2AMEN1L3MBTL1NOS3NOS2 | |
| SCHEMBL9770020 | 0.70 | GRIN2D (0.43) | KMT2ANOS3NOS2NOS1ALDH1A1 | |
| SCHEMBL13473988 | 0.70 | ATM (0.46) | KMT2APSMB5NOS3NOS2NOS1 | |
| SCHEMBL13197746 | 0.70 | ATM (0.42) | KMT2AMEN1PSMB5KDM4EALDH1A1 | |
| SCHEMBL14488757 | 0.70 | PSMB5 (0.44) | KMT2AMEN1PSMB5ATMNPC1 | |
| SCHEMBL15581736 | 0.70 | ATM (0.54) | KMT2AMEN1PSMB5KDM4EALDH1A1 | |
| SCHEMBL834352 | 0.68 | KDM4E (0.45) | KMT2AMEN1L3MBTL1PSMB5KDM4E | |
| SCHEMBL10392532 | 0.68 | NOS3 (0.39) | NOS3NOS2NOS1ALDH1A1HIF1A | |
| SCHEMBL22165787 | 0.68 | KDM4E (0.41) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |