Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 4/20 | 0.36 |
| ▸ | HEXB | P07686 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38663353 | 0.79 | HEXA (0.41) | MAPK1SMN1; SMN2HEXAHEXBALDH1A1 | |
| SCHEMBL22165745 | 0.79 | TSHR (0.37) | MAPK1MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL22165787 | 0.79 | KDM4E (0.41) | MAPK1MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL16414754 | 0.78 | NOS3 (0.34) | KMT2ASMN1; SMN2ALDH1A1KDM4ENOS3 | |
| SCHEMBL13925721 | 0.75 | RAPGEF4 (0.38) | L3MBTL1 | |
| SCHEMBL24312322 | 0.74 | CFTR (0.39) | MAPK1L3MBTL1SMN1; SMN2HEXAHEXB | |
| SCHEMBL19595007 | 0.74 | — | — | |
| SCHEMBL694204 | 0.74 | NOS3 (0.41) | MAPK1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20146924 | 0.73 | KMT2A (0.42) | MEN1KMT2AL3MBTL1HEXAHEXB | |
| SCHEMBL22961027 | 0.73 | MEN1 (0.36) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |